Vitamin D enhances responses to interferon-β in MS
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چکیده
منابع مشابه
Vitamin D in MS: a vitamin for 4 seasons.
OBJECTIVE: There is increasing evidence that vitamin D can be protective against the development of multiple sclerosis (MS), but it may also be beneficial for the clinical course of the disease. Our objective was to prospectively investigate if 25-hydroxy-vitamin D (25OH-D) levels are associated with exacerbation risk in MS in a study with frequent serum measurements. METHODS: This was a prospe...
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OBJECTIVE Studies based on deseasonalized vitamin D levels suggest that vitamin D may influence the disease activity in multiple sclerosis (MS), and high doses are suggested as add-on treatment to interferon-β (IFN-β). Seasonal fluctuation of vitamin D varies between individuals, thus the relationship to disease activity should preferentially be studied by repeated and simultaneous vitamin D an...
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Interferon (IFN)-alpha/beta and interleukin (IL)-12 are cytokines critical in defense against viruses, but their cellular sources and mechanisms of regulation for in vivo expression remain poorly characterized. The studies presented here identified a novel subset of dendritic cells (DCs) as major producers of the cytokines during murine cytomegalovirus (MCMV) but not lymphocytic choriomeningiti...
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ژورنال
عنوان ژورنال: Neurology - Neuroimmunology Neuroinflammation
سال: 2019
ISSN: 2332-7812
DOI: 10.1212/nxi.0000000000000622